The phage shock protein response
WebbThe Psp response was discovered by Peter Model and his colleagues at the Rockefeller University in New York City. They noticed that infection of Escherichia coli cells by the filamentous phage f1 and production of the phage-encoded secretin (a pore-forming protein) caused massive production of a bacterial protein they called PspA [ 8 ]. WebbThe temperature-sensitive bacteriophage λ c 1857 repressor protein rapidly renatures after thermal inactivation. E. coli mutants in the heat shock protein genes dnaK, dnaJ , and grpE do not efficiently reactivate heat-denatured repressor. Our results suggest that protein refolding is promoted by heat shock proteins and that such a process is the basis of the …
The phage shock protein response
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Webb1 mars 2024 · One mechanism for maintaining envelope integrity is the phage-shock-protein (Psp) response, a multigene system involving a cascade of protein interactions … Webb1 sep. 2005 · The phage-shock-protein (Psp) system responds to extracytoplasmic stress that may reduce the energy status of the cell. It is conserved in many different bacteria and has been linked to...
WebbThe phage-shock-protein (Psp) system of Yersinia enterocolitica encodes a stress response that is essential for viability when the secretin component of its Ysc type III secretion system is produced. Therefore, Y. enterocolitica psp null mutants are completely avirulent in a mouse model of infection. This article summarizes what is known about … Webb30 juni 2005 · The phage-shock-protein response Introduction. The Gram-negative bacterial cell envelope controls the passage of molecules into and out of the cell,...
WebbPhage shock proteins (Psp) and their homologues are found in species from the three domains of life: Bacteria, Archaea and Eukarya (e.g. higher plants). In enterobacteria, the … WebbThe phage shock protein (Psp) system was identified as a response to phage infection in Escherichia coli, but rather than being a specific response to a phage, it detects and …
WebbThe phage shock protein (Psp) stress response is one such conserved protection network. Most knowledge about the Psp response derives from studies in the Gram-negative …
WebbThe phage shock protein (Psp) system is a conserved extracytoplasmic stress response in bacteria that is essential for virulence of the human pathogen Yersinia enterocolitica. … hile water antiWebbThe Phage shock protein (Psp) response is an extracytoplasmic stress response. The central component of this system is PspA, a protein that mediates the physiological response to membrane stress. PspA is also involved in regulating its own transcription and that of the psp operon, forming a positive feedback loop. PspA has been previously … hile v michiganWebbThe phage shock protein (Psp) F regulon response in Escherichia coli is thought to be induced by impaired inner membrane integrity and an associated decrease in proton motive force (pmf). Mechanisms by which the Psp system detects the stress signal and responds have so far remained undetermined. Here we demonstrate that PspA and PspG directly … hile oneWebb8 nov. 2010 · In Escherichia coli, the phage shock protein (Psp) stress response system is responsible for repairing damage to the inner membrane of the cell ( Kobayashi et al. 2007) and maintenance of the proton-motive force (pmf) across the inner membrane (reviewed in Model et al. 1997; Darwin 2005; Jovanovic et al. 2006 ). hile v state of michiganWebb31 dec. 2004 · The phage shock protein operon (pspABCDE) of Escherichia coli is strongly up-regulated in response to overexpression of the filamentous phage secretin protein IV … hile-best funeral home seneca paWebb15 feb. 2024 · The phage shock protein (Psp) stress-response system protects bacteria from envelope stress through a cascade of interactions with other proteins and membrane lipids to stabilize the cell membrane. hile waterWebb(Figure 1). Filamentous phage infection induces pspA operon expression because a phage-encoded outer membrane pore-forming ‘‘secretin’’ protein (pIV) has a tendency to … hile the world